Water bottles will fit loosely but humidifier will function without any problems. No cleansing or sanitizing needed. USB cable included. Can be used in the car when the aire is dry from heater or air conditioner. Can be used as a mist when hydration is needed. Can be used as a night light. Can be used to 6~8 hours with 10-16 fl oz of bottled water on USB cable or smart phone charger.